A Review : Formulation And Evaluation Of Cissus Quandrangularis Ointment For The Treating Fracture Bone Healing

• Author(s):

  U.Thendralarasi | K.Malarvizhi

• Keywords:

  Cissus Quadrangularis, Fracture Healing, Bone Regeneration, Herbal Ointment, Osteogenesis, Phytotherapy.

• Abstract:

  Cissus Quadrangularis Is A Medicinal Plant Traditionally Used In Ayurvedic Medicine For Its Bone-healing Properties. The Plant Contains Bioactive Compounds Such As Ketosterones, Flavonoids, And Triterpenoids, Which Are Believed To Stimulate Bone Formation And Accelerate Fracture Healing. When Formulated Into An Ointment, Cissus Quadrangularis Can Be Applied Topically Over The Fracture Site To Enhance Local Bone Regeneration, Reduce Inflammation, And Promote Quicker Recovery. Studies Suggest That Such Ointments May Support Callus Formation And Improve The Biomechanical Strength Of Healing Bones, Offering A Complementary Therapy To Conventional Fracture Treatment. Cissus Quadrangularis Ointment For Treating Fracture Bone Healing. Cissus Quadrangularis (CQ), A Traditional Medicinal Plant Widely Used In Ayurveda, Has Been Reputed For Its Bone-healing Properties. Rich In Vitamins, Steroids, And Anabolic Steroidal Substances, CQ Is Known To Enhance Fracture Healing Through Stimulation Of Osteoblast Activity And Reduction Of Inflammation. While Oral Formulations Have Been Well-documented, Topical Applications Such As Ointments Are Gaining Attention For Localized And Targeted Therapeutic Benefits.Cissus Quadrangularis Has Gained Attention As A Natural Therapeutic Agent For Enhancing Bone Fracture Healing, Often Compared With Conventional Treatments Such As Calcium Supplements, Vitamin D, And Other Pharmacological Agents. Studies Have Demonstrated That Cissus Quadrangularis Not Only Accelerates The Healing Process But Also Improves Bone Strength And Mineralization More Effectively Than Standard Therapies Alone. Its Phytochemical Components—such As Ketosteroids, Flavonoids, And Calcium—contribute To Osteoblastic Activity And Collagen Synthesis, Which Are Essential For Bone Regeneration. Compared To Placebo Or Standard Calcium Therapy, Patients And Animal Models Treated With Cissus Quadrangularis Often Show Reduced Healing Time, Better Callus Formation, And Improved Clinical Outcomes. While Preliminary Results Are Promising, Further Comparative Clinical Trials Are Needed To Fully Validate Its Effectiveness And Integrate It Into Mainstream Orthopedic Care.

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Other Details

• Paper id:

  IJSARTV11I8103986

• Published in:

  Volume: 11 Issue: 8 August 2025

• Publication Date:

  2025-08-25

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